The ketogenic diet is best known as a high-fat, low-carbohydrate diet commonly used to treat drug-resistant epilepsy in children. Despite a ketogenic diet therapy’s ability to suppress refractory epilepsies for over a century, the underlying mechanisms of the ketogenic diet remain enigmatic. While the exact ketogenic diet mechanisms of action are not yet known, several…
Read more
According to recommendations made by international diabetes guidelines, the therapy of type 2 diabetes mellitus entails both pharmaceutical and lifestyle changes [1, 2, 3] Nutritional recommendations frequently emphasize cutting back on excess carbohydrates and restricting fat intake to 20–35% of total calories, with a particular emphasis on reducing saturated fats. Conversely, some diets advocate substantially…
Read more
For many people on the ketogenic diet, enjoying a glass of wine or a few beers with some friends might have been a regular part of our past social lives. The 10-15 grams of carbohydrates in a normal bottle of beer, however, will obviously take up a notable portion of your carbohydrate “budget”, especially if…
Read more
Alcohol is one of the oldest and most widely consumed recreational psychoactive substances, and as we’ve argued previously, alcohol is clearly a part of an ancestral-type diet. By potentiating the effects of the gamma-aminobutyric (GABA) neurotransmitter and the binding to its receptor (GABA-A), it induces feelings of relaxation, euphoria, and decreases anxiety, among other cognitive…
Read more
Forty years after its first introduction, the high-performance anion-exchange with pulsed amperometric detection ( HPAEC-PAD ) method is a well-established technique used for separating and quantifying a broad range of carbohydrates. HPAEC-PAD has replaced many of the methods used for carbohydrate analysis 40 years ago, and there are innumerable reasons for the acceptance and popularity of HPAEC-PAD…
Read more
Paolo Raggi MD: A Critical View of of the Keto Diet
Read more