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What is Allulose?  Everything you need to know in 300 words or less

What is Allulose? Everything you need to know in 300 words or less

June 23, 2021 991 views

What is allulose?  Allulose is a low-calorie (0.2 kcal/g) monosaccharide present in some foods in very small amounts, and is currently mass-produced through enzymatic conversion of fructose (the enzyme tagatose 3-epimerase converts fructose to allulose).

It has been considered a therapeutic agent towards metabolic syndrome and type-II diabetes due to having antioxidant effects, inhibitory activity toward brush-border digestive enzymes, competes with glucose for entry into intestinal cells, and increases glucose uptake into the liver.

In individuals with type-II diabetes, consuming 5 and 10 grams of allulose alongside a 75-gram oral glucose tolerance test (OGTT) significantly reduced the peak and overall glucose response in a linear dose-response manner. Insulin was also reduced with the 10-gram dose. When this study was repeated in healthy adults, a small reduction in glucose but not insulin was observed.

Allulose (5 grams) marginally enhances fat oxidation in healthy adults when consumed before a standardized meal, and a 12-week intervention in normal-weight and overweight Korean adults reported that taking two 4-gram or 7-gram doses of allulose per day significantly reduced body weight and body fat mass, mostly from the subcutaneous depots (rather than visceral).

A dose-escalation study found that no gastrointestinal complaints were observed with the consumption of allulose until a single dose reached 0.4 g/kg body weight, which resulted in abdominal pain and diarrhea.

 

 

PaleoNot Paleo
Naturally occurring “rare” sugar very low in caloriesIsolated molecule that would be consumed in quantities never before experienced
Has metabolic benefits with no known risksDerived from corn in commercial forms
Similar to other paleo-approved sweeteners like monk fruit

Verdict: Not Eligible for Certified Paleo

 

KetoNot Keto
Minimal caloriesIsolated molecule that would be consumed in quantities never before experienced
Enhances fat oxidation
Benefits glycemic control
Low-carb sweetener

Verdict: Eligible for Keto Certified

 

Grain-FreeNot Grain-Free
Does not contain zein prolamin fractionIsolated molecule from corn
Corn ethanol is allowed in the Grain-Free program because it does not contain the prolamin fractions.

Verdict: Eligible for Grain-Free Certification

 

 

 

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Karen Pendergrass

Karen Pendergrass

ENTP polemicist and enthusiast in a myriad of areas including agricultural sustainability, applications of bacteriotherapy, autoimmunity, color theory, hard determinism, gut microbiome, fiber, antioxidants, and psychology. Founder of The Paleo Foundation and Cetogenica.com. Agnostic in general— except for I know with certainty that pineapples do not belong on pizza.

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